The research at the Research Division of Molecular Metabolism focuses on
mitochondrial genetics and the impact of mitochondrial dysfunction on disease and
ageing. Our research delves into the maintenance and regulation of mitochondrial
DNA, including its transcription and translation processes. We also investigate how
mitochondrial function is controlled and what occurs when this function is impaired.
The division has a close collaboration with the Centre for Inherited Metabolic
Diseases at Karolinska University Hospital enhancing our ability to translate
scientific insights into clinical impact.
We offer master student, PhD and Postdoc positions to highly motivated and enthusiastic
researchers.
For
details, please, contact us by email .
Nils-Göran Larsson
The small-molecule inhibitors (green) target the expression of mitochondrial DNA and
cause a cellular energy crisis in cancer cells to stop their growth.
Illustration by Mattias Karlén.
Anna Wredenberg
Mitochondrial network in cultured human cells.
Photo by D.Alsina
Joanna Rorbach
Structure of the human mitochondrial ribosome (PDB
3J9M).