The Filograna group is interested in understanding how mitochondrial dysfunction affects identity, function and survival of the different cell type of the central nervous system. Our research focuses on the impact of mitochondrial fitness in cell autonomous and non-autonomous mechanisms of neurodegeneration, with a special focus on Parkinson’s disease. We employ genetic, molecular and omics approaches and use in vitro and in vivo models to dissect the molecular events driving neuronal cell death. In the long-term, we hope that our studies will identify druggable targets and set the ground for novel therapeutic avenues to treat neurodegenerative disorders.
Junior group leader
PhD student
Postdoc
Research assistant
Master student
Division of Molecular Metabolism
Biomedicum 9D
Solnavägen 9
17165 Solna
Sweden
